I Wanna Hold Your Strands
(to the tune of "I Wanna Hold Your Hand")
Copyright © 2011 Kevin Ahern
Oh yeah, I’ll tell you something
It helps to understand
Pol III de-crees
To meet the cell’s demands
It has to hold the straaaaaands
It’s gotta hold the strands
The key, Pol III
Acts most processively
‘Cuz see, Pol III
Has beta clamping ha-a-a-a-ands
It uses beta’s ba-a-a-a-a-a-ands (note this is ‘bands,’ not ‘hands’)
To hold onto the strands
As it starts rep-li-CAT-ING a d---N-A (emphasis as noted)
The un-win-DING requires a lone
Helicase
Helicase
Helica-a-a-a-a-a-a-ase!
Pri-mase starts the primer
That Pol I can erase
Pol III takes the primer
And starts the DNAs
It starts the DNA-a-a-a-as
By using RNA
And when a fragment Okazaki - displays
There must be joining
That requires
A ligase
A ligase
A liga-a-a-a-ase
Thanks to all the factors
And all of their ligands
The cell has what matters
To replicate the strands
It replicates the strands
It replicates the strands
It replicates the stra-a-a-a-a-a-a-a-ands
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