The Citric Acid Cycle

Copyright © 2011 Kevin Ahern

 

I love my citrate synthase

It really is first rate

Adds O-A-A to Ac-Co-A

Producing a citrate

 

Aconitase is picky

Binds substrates specially

Creating isocitrate

Which has no symmetry

 

Then CO2 gets lost from it

Released in the next phase

The secret weapon - Isocitrate

Dehydrogenase

 

The alpha K –DH is next

It gets my admiration

For clipping CO2 in one more

Decarboxylation

 

Succ-CoA synthetase steps up

Reacting most absurd

ItŐs named for a catalysis

That really goes backward

 

Suc -CIN-ate de-hyd-ROG-en-ase

Pulls H from succinate

Creating FADH2

As well as fumarate

 

The fumarate gains water

OH-configured L

ItŐs fumaraseŐs product

Some malate for the cell

 

With the last oxidation

Malate de-hyd-ROG-en-ase

Expels its two creations

N-A-D-H / O-A-A

 

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